Johannes Möller, Dr Ing

Hamburg University of Technology, Institute of Bioprocess&Biosystems Engineering
Research Associate
Johannes Möller, Dr Ing, works as a scientist at the Institute of Bioprocess and Biosystems Engineering (TUHH). His research focus is on accelerated and knowledge-driven bioprocess design and optimization using novel statistical and computational methods. The main areas of his research are on biosys-tems engineering, software development for model-assisted bioprocess development and experimental design, and computational methods for biopro-cess characterization and control.

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Figure 1: General workfl ow for the application of model-assisted DoE (mDoE).
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Mathematical Models in Experimental Design and Scale-up

The implementation of a mammalian cell-based biopharmaceutical manufacturing process demands robust methods for knowledge handling, from early-stage development and technology transfer to production scale. Mathematical process modeling can summarize this knowledge as the relationships of critical quality attributes to critical process parameters using mathematical equations and sound...